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Beyond the three widely recognized TBA metabolites, little is known about other metabolites formed. Online shops, our shopping basket system relies on the use of cookies. Effects of GCS are explained by three broad molecular mechanisms: the decreased expression of pro-inflammatory genes (trans-repression), the increased expression of anti-inflammatory genes (trans-activation), and non-genomic mechanisms. Therapy is the medically supervised administration of testosterone (or medications that boost testosterone) to men who have low blood levels of testosterone.

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