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This H-bonding motif in our previous paper was indicated as an essential signature of drug-efficacy. Erythromycin may inhibit the metabolism of some corticosteroids. An example of a SERM with high IA and thus mostly estrogenic effects is chlorotrianisene , while an example of a SERM with low IA and thus mostly anti-estrogenic effects is ethamoxytriphetol. Testicular Atrophy Assay: Administering testosterone to non-castrated rats causes a decrease in serum levels of gonadotropins. The nature of Deca-Durabolin, side effects cannot be quickly reversed by discontinuing medication.

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